FABP2 Polyclonal Antibody

Background:
The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance.

Research Area: Cancer, Cardiovascular, Metabolism, Developmental Biology, Signal Transduction, Stem Cells

Synonyms:
FABP2, FABPI, I-FABP

Immunogen: Recombinant fusion protein of human FABP2 (NP_000125.2).

Swissprot: P12104
Gene ID: 2169

Calculated MW: 15 kDa
Observed MW: 15 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:10-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.