AID polyclonal, anti-human, mouse, rat
€470.00
In stock
SKU
AC-AP73749
Background:
Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation (SHM), gene conversion, and class-switch recombination (CSR) in B-lymphocytes by deaminating C to U during transcription of Ig-variable (V) and Ig-switch (S) region DNA. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses (PubMed:18722174, PubMed:21385873, PubMed:21518874, PubMed:27716525). May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation (PubMed:21496894).
Other Names:
AICDA; AID; Activation-induced cytidine deaminase; Cytidine aminohydrolase
Antigen Type: synthetic peptide
Antigen Type: AICDA
Gene ID: 57379
Primary Accession: Q9GZX7
Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation (SHM), gene conversion, and class-switch recombination (CSR) in B-lymphocytes by deaminating C to U during transcription of Ig-variable (V) and Ig-switch (S) region DNA. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses (PubMed:18722174, PubMed:21385873, PubMed:21518874, PubMed:27716525). May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation (PubMed:21496894).
Other Names:
AICDA; AID; Activation-induced cytidine deaminase; Cytidine aminohydrolase
Antigen Type: synthetic peptide
Antigen Type: AICDA
Gene ID: 57379
Primary Accession: Q9GZX7
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