Factor VII polyclonal, anti-human

Quantity: 100 µg

Background:
F7(Coagulation Factor VII), also known as proconvertin, is one of the proteins that causes blood to clot in the coagulation cascade. It is an enzyme of the serine protease class. The F7 gene maps to chromosome 13q34(Millar et al., 2000). Synthesis of factors VII and X, as well as factors II and IX, takes place in the liver and requires vitamin K. Structural homologies of these factors, which are precursors of serine proteases, have been shown(Zur and Nemerson, 1981). Di Bitondo et al.(2002) used reporter gene analysis to show that inclusion of promoter regions of F7 reduced transcription activity in the presence of estrogenic factors. The effect was independent of promoter polymorphic haplotype.

Description:
Rabbit IgG polyclonal antibody for Coagulation factor VII (F7) detection. Tested with WB in Human.

Synonyms:
coagulation factor VII(serum prothrombin conversion accelerator) antibody, Coagulation factor VII antibody, Eptacog alfa antibody, F7 antibody, FA7_HUMAN antibody, Factor VII antibody, Factor VII heavy chain antibody, Factor VII light chain antibody, FVII coagulation protein antibody, OTTHUMP00000018733 antibody, OTTHUMP00000018734 antibody, Proconvertin antibody, Serum prothrombin conversion accelerator antibody, SPCA antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Factor VII(441-453aa SQYIEWLQKLMRS).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.