Factor VIII polyclonal, anti-human

Quantity: 100 µg

Background:
Coagulation Factor VIII(FVIII) is an essential blood-clotting protein, also known as anti-hemophilic factor(AHF). By in situ hybridization, Tantravahi et al.(1986) concluded that the F8 gene is located in the proximal part of chromosome Xq28 with probes DX13 and St14 distally located. The F8 gene encodes coagulation factor VIII, a large plasma glycoprotein that functions in the blood coagulation cascade as a cofactor for the factor IXa-dependent activation of factor X(F10). Factor VIII is activated proteolytically by a variety of coagulation enzymes, including thrombin(F2). Factor VIII is tightly associated in the blood with von Willebrand factor(VWF), which serves as a protective carrier protein for factor VIII(Toole et al., 1984; Hoyer, 1994).

Description:
Rabbit IgG polyclonal antibody for Coagulation factor VIII (F8) detection. Tested with WB in Human.

Synonyms:
Ahf antibody, Antihemophilic factor antibody, Coagulation factor VIII antibody, Coagulation factor VIII associated protein b antibody, Coagulation factor VIII isoform b antibody, Coagulation factor VIII procoagulent component antibody, coagulation factor VIII, procoagulant component antibody, Coagulation factor VIIIc antibody, Dna segment on chromosome x unique 1253 expressed sequence antibody, Dxs1253e antibody, F8 antibody, F8 protein antibody, F8b antibody, F8c antibody, FA8_HUMAN antibody, Factor VIII F8b antibody, Factor VIIIa light chain antibody, FactorVIII antibody, FVIII antibody, Hema antibody, Hema coagulation factor VIIIc procoagulent component antibody, Hemophilia a antibody, Hemophilia classic antibody, Hemophilia, classic antibody, OTTHUMP00000061446 antibody, OTTHUMP00000196174 antibody, Procoagulant component antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human Factor VIII(1264-1278aa APVLQDFRSLNDSTN).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.