FADD monoclonal, anti-human

Description: Anti-FADD Monoclonal Antibody . Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human.

Other Names: FAS-associated death domain protein, FAS-associating death domain-containing protein, Growth-inhibiting gene 3 protein {ECO:0000303|Ref.3}, Mediator of receptor induced toxicity, FADD {ECO:0000303|PubMed:7538907, ECO:0000312|HGNC:HGNC:3573}

Clone Name(s):
Clone: ADDB-6

Gene ID: 8772

Immunogen: A synthesized peptide derived from human FADD Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.

Calculated MW: 23279

Purification: Affinity-chromatography

Format: Liquid

Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.