FADD polyclonal, anti-human

Quantity: 100 µg

Background:
FADD, Fas-Associated protein with Death Domain, is a universal adaptor protein in apoptosis that mediates signaling of all known death domain-containing members of the TNF receptor superfamily. The FADD gene contains 2 exons and spans approximately 3.6 kb. By analysis of somatic cell hybrid panels and by fluorescence in situ hybridization, the FADD gene is mapped to 11q13.3. The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, thus, it participates in the death signaling initiated by these receptors.

Description:
Rabbit IgG polyclonal antibody for Protein FADD (FADD) detection. Tested with WB in Human.

Synonyms:
FADD antibody, FADD protein antibody, FADD_HUMAN antibody, Fas(TNFRSF6) associated via death domain antibody, Fas associated via death domain antibody, Fas associating death domain containing protein antibody, Fas associating protein antibody, Fas associating protein with death domain antibody, Fas TNFRSF6 associated via death domain antibody, FAS-associated death domain protein antibody, FAS-associating death domain-containing protein antibody, FasTNFRSF6 associated via death domain antibody, GIG 3 antibody, GIG3 antibody, Growth inhibiting gene 3 protein antibody, Growth-inhibiting gene 3 protein antibody, H sapiens mRNA for mediator of receptor induced toxicity antibody, Mediator of receptor induced toxicity antibody, MGC8528 antibody, MORT 1 antibody, MORT1 antibody, Protein FADD antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human FADD(174-189aa ADLVQEVQQARDLQNR).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.