FADD rabbit polyclonal, anti-mouse

Backgroud: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.

Synonyms: FADD protein, GIG3, Growth inhibiting gene 3 protein, Mediator of receptor induced toxicity, MORT1

Gene Name: Fadd

Gene ID: 14082

SwissProt ID: Q61160

Purification: Affinity Chromatography

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.