FAM175A Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP9636c
Background:
Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it acts as a central scaffold protein that assembles the various components of the BRCA1-A complex and mediates the recruitment of BRCA1.
Other Names:
BRCA1-A complex subunit Abraxas, Coiled-coil domain-containing protein 98, Protein FAM175A, FAM175A, ABRA1, CCDC98
Gene Name: ABRAXAS1 (HGNC:25829)
Gene ID: 84142
Primary Accession: Q6UWZ7
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it acts as a central scaffold protein that assembles the various components of the BRCA1-A complex and mediates the recruitment of BRCA1.
Other Names:
BRCA1-A complex subunit Abraxas, Coiled-coil domain-containing protein 98, Protein FAM175A, FAM175A, ABRA1, CCDC98
Gene Name: ABRAXAS1 (HGNC:25829)
Gene ID: 84142
Primary Accession: Q6UWZ7
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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