FANCA polyclonal, anti-human, mouse

FANCA polyclonal, anti-human, mouse

€362.00
In stock
SKU
200161
Catalog Nr.: 200161
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB
Datasheet
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Protein Family: Enzymes

Pathway and Disease: Cancers, Replication and Repair

Description:
Fanconi anemia group A protein (FANCA) is a DNA repair protein that operates in a postreplication repair or a cell cycle checkpoint function. FANCA is involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Defects in FANCA are the cause of Fanconi anemia, a syndrome characterized by pancytopenia, congenital malformations and predisposition to cancers caused by a hypersensitivity to DNA-damaging agents, chromosomal instability and defective DNA repair.

Alternate Names: Fanconi anemia group A protein, Protein FACA, FANCA, FAA, FACA, FANCH

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500

Accession No.: O15360, NP_000126

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human FANCA.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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