FANCA polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP18008C
Catalog Number: AC-AP18008C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB23899
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB23899
Applications: WB
Datasheet
Request Information
Background:
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia.
Other Names:
Fanconi anemia group A protein, Protein FACA, FANCA, FAA, FACA, FANCH
Target/Specificity:
This FANCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 667-694 amino acids from the Central region of human FANCA.
Antigen Region:
667-694
Antigen Type: Synthetic Peptide
Gene Name: FANCA
Gene ID: 2175
Primary Accession: O15360
NCBI Accession: NP_000126.2;NP_001018122.1
Other Accession: NP_000126.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia.
Other Names:
Fanconi anemia group A protein, Protein FACA, FANCA, FAA, FACA, FANCH
Target/Specificity:
This FANCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 667-694 amino acids from the Central region of human FANCA.
Antigen Region:
667-694
Antigen Type: Synthetic Peptide
Gene Name: FANCA
Gene ID: 2175
Primary Accession: O15360
NCBI Accession: NP_000126.2;NP_001018122.1
Other Accession: NP_000126.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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