FANCD2 Blocking Peptide (Center)
€363.00
In stock
SKU
AC-BP21536c
Background:
Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress. Promotes BRCA2/FANCD1 loading onto damaged chromatin. May also be involved in B-cell immunoglobulin isotype switching.
Other Names:
Fanconi anemia group D2 protein, Protein FACD2, FANCD2, FACD
Target/Specificity:
The synthetic peptide sequence is selected from aa 893-907 of HUMAN FANCD2
Gene Name: FANCD2
Gene ID: 2177
Primary Accession: Q9BXW9
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress. Promotes BRCA2/FANCD1 loading onto damaged chromatin. May also be involved in B-cell immunoglobulin isotype switching.
Other Names:
Fanconi anemia group D2 protein, Protein FACD2, FANCD2, FACD
Target/Specificity:
The synthetic peptide sequence is selected from aa 893-907 of HUMAN FANCD2
Gene Name: FANCD2
Gene ID: 2177
Primary Accession: Q9BXW9
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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