FANCD2 (Center) RB49367 polyclonal, anti-human
€144.00
In stock
SKU
AC-AP21536c
Catalog Number: AC-AP21536c
Size: 80 µl
Other Size: 80 µl
Host: Rabbit Ig
Applications: WB
Datasheet
Request Information
Size: 80 µl
Other Size: 80 µl
Host: Rabbit Ig
Applications: WB
Datasheet
Request Information
Background:
Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress. Promotes BRCA2/FANCD1 loading onto damaged chromatin. May also be involved in B-cell immunoglobulin isotype switching.
Other Names: Fanconi anemia group D2 protein, Protein FACD2, FANCD2, FACD
Target/Specificity:
This FANCD2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 893-927 amino acids from the Central region of human FANCD2.
Dilution: 1:2000
Calculated MW: 164128
Gene Name: FANCD2
Gene ID: 2177
Primary Accession: Q9BXW9
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress. Promotes BRCA2/FANCD1 loading onto damaged chromatin. May also be involved in B-cell immunoglobulin isotype switching.
Other Names: Fanconi anemia group D2 protein, Protein FACD2, FANCD2, FACD
Target/Specificity:
This FANCD2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 893-927 amino acids from the Central region of human FANCD2.
Dilution: 1:2000
Calculated MW: 164128
Gene Name: FANCD2
Gene ID: 2177
Primary Accession: Q9BXW9
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
|---|
Write Your Own Review