FANCL polyclonal(C-term), anti-human

FANCL polyclonal(C-term), anti-human

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In stock
SKU
AC-AP19508b
Catalog Number: AC-AP19508b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB23901
Applications: WB
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Background:
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms.

Other Names:
E3 ubiquitin-protein ligase FANCL, 632-, Fanconi anemia group L protein, Fanconi anemia-associated polypeptide of 43 kDa, FAAP43, FANCL, PHF9

Target/Specificity:
This FANCL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-302 amino acids from the C-terminal region of human FANCL.

Antigen Region:
274-302

Antigen Type: Synthetic Peptide

Gene Name: FANCL
Gene ID: 55120
Primary Accession: Q9NW38
NCBI Accession: NP_001108108.1;NP_060532.2
Other Accession: NP_001108108.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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