FARSLB polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60426
Background:
FARSLB (Phenylalanine--tRNA ligase beta chain), also known as FARSB, FRSB, PheHB or PheRS, is a 589 amino acid cytoplasmic protein that is the regulatory beta subunit of phenylalanine-tRNA synthetase. A highly conserved member of the aminoacyl-tRNA synthetase class IIc subfamily, FARSLB functions to enzymatically attach L-phenylalanine residues to terminal adenosines on tRNA(Phe). This is an ATP-dependent reaction that yields AMP, a diphosphate and an L-phenylalanine-tagged tRNA(Phe). FARSLB is expressed in brain, heart, kidney, pancreas, placenta and skeletal muscle and its expression is increased in malignant cell lines, suggesting a possible role for FARSLB in carcinogenesis.
Alternative Name:
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS, FARSB, FARSLB, FRSB, HSPC173
Application Dilution: WB: 1:500~1:1000
Specificity: FARSLB polyclonal antibody detects endogenous levels of FARSLB protein.
Immunogen:
A synthetic peptide corresponding to residues in Human FARSLB.
MW: ~ 70 kDa
Swis Prot.: Q9NSD9
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
FARSLB (Phenylalanine--tRNA ligase beta chain), also known as FARSB, FRSB, PheHB or PheRS, is a 589 amino acid cytoplasmic protein that is the regulatory beta subunit of phenylalanine-tRNA synthetase. A highly conserved member of the aminoacyl-tRNA synthetase class IIc subfamily, FARSLB functions to enzymatically attach L-phenylalanine residues to terminal adenosines on tRNA(Phe). This is an ATP-dependent reaction that yields AMP, a diphosphate and an L-phenylalanine-tagged tRNA(Phe). FARSLB is expressed in brain, heart, kidney, pancreas, placenta and skeletal muscle and its expression is increased in malignant cell lines, suggesting a possible role for FARSLB in carcinogenesis.
Alternative Name:
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS, FARSB, FARSLB, FRSB, HSPC173
Application Dilution: WB: 1:500~1:1000
Specificity: FARSLB polyclonal antibody detects endogenous levels of FARSLB protein.
Immunogen:
A synthetic peptide corresponding to residues in Human FARSLB.
MW: ~ 70 kDa
Swis Prot.: Q9NSD9
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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