FAS-Associated Phosphatase (FAP-1) polyclonal, anti-human

Quantity: 200 µl

Description:
A novel protein tyrosine phosphatase, FAP-1 (for FAS-associated phosphatase) (originally designated PTP-BAS), has been shown to associated with the carboxy terminus fifteen amino acids of FAS. Three isoforms of the protein result from alternative RNA splicings, the longest of which encodes a protein 2485 amino aicds in lenghth. Although lacking a transmembrane region, FAP-1 does contain a membrane-binding domain, similar to that found in cytoskeleton-associated proteins such as ezrin. FAP-1 does not seem to associate with CD40 or death domain proteins such as TNF-RI and TNF-RII.

Isotype: Rabbit Polyclonal IgG

Immunogen:
Recombinant protein encoding aa 2290-2491 of human FAP-1.

Form: Affinity purified, in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

Reactivity: human

Applications: IHC-P

Working DIlution: IHC: 1:100

Positive Control:
Colon Carcinoma, Placenta

Storage: 2-8C for immediate use. -20C for long term.