Fas (clone 4C3) mouse monoclonal, anti-human

Backgroud: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.

Synonyms: FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6

Gene Name: FAS

Gene ID: 355

SwissProt ID: P25445

Purification: Affinity Purified

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.