FAS polyclonal, anti-mouse, rat
€455.00
In stock
SKU
AC-ABO10576
Catalog Number: AC-ABO10576
Size: 100 µg
Isotype: Rabbit IgG
Applications: WB, IHC-P, IHC-F
Datasheet
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Size: 100 µg
Isotype: Rabbit IgG
Applications: WB, IHC-P, IHC-F
Datasheet
Request Information
Description: Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 6(FAS) detection. Tested with WB, IHC-P, IHC-F in Mouse;Rat.Protein Name: Tumor necrosis factor receptor superfamily member 6
Protein Function:
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death- inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS- mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity). .
Other Names: Tumor necrosis factor receptor superfamily member 6, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, FASLG receptor, CD95, Fas, Apt1, Tnfrsf6
Subcellular Localization: Membrane; Single-pass type I membrane protein.
Gene ID: 246097
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of rat Fas (87-109aa, YTDRKHYSDKCRRCAFCDEGHGL).
Calculated MW: 36835
Purification: Immunogen affinity purified.
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Concentration (mg/ml): Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Protein Function:
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death- inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS- mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity). .
Other Names: Tumor necrosis factor receptor superfamily member 6, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, FASLG receptor, CD95, Fas, Apt1, Tnfrsf6
Subcellular Localization: Membrane; Single-pass type I membrane protein.
Gene ID: 246097
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of rat Fas (87-109aa, YTDRKHYSDKCRRCAFCDEGHGL).
Calculated MW: 36835
Purification: Immunogen affinity purified.
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Concentration (mg/ml): Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
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