FASN antibody (clone 3F2-1F3), anti-human
€435.00
In stock
SKU
AC-AT2002a
Catalog Number: AC-AT2002a
Size: 50 µg
Isotype: mouse IgG1 kappa
Applications: WB, IHC, IF, IP
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Size: 50 µg
Isotype: mouse IgG1 kappa
Applications: WB, IHC, IF, IP
Request Information AC-AT2002a">Request Information
Background:
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
Other Names:
Fatty acid synthase, [Acyl-carrier-protein] S-acetyltransferase, [Acyl-carrier-protein] S-malonyltransferase, 3-oxoacyl-[acyl-carrier-protein] synthase, 3-oxoacyl-[acyl-carrier-protein] reductase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase, Enoyl-[acyl-carrier-protein] reductase, Oleoyl-[acyl-carrier-protein] hydrolase, FASN, FAS
Antigen Type:
Recombinant Protein
Gene Name: FASN
Gene ID: 2194
NCBI Accession: NP_004095.4
Primary Accession: P49327
Other Accession: BC007909
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
Other Names:
Fatty acid synthase, [Acyl-carrier-protein] S-acetyltransferase, [Acyl-carrier-protein] S-malonyltransferase, 3-oxoacyl-[acyl-carrier-protein] synthase, 3-oxoacyl-[acyl-carrier-protein] reductase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase, Enoyl-[acyl-carrier-protein] reductase, Oleoyl-[acyl-carrier-protein] hydrolase, FASN, FAS
Antigen Type:
Recombinant Protein
Gene Name: FASN
Gene ID: 2194
NCBI Accession: NP_004095.4
Primary Accession: P49327
Other Accession: BC007909
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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