FAT1 Polyclonal Antibody
€0.00
In stock
SKU
ELK-ES9143
Catalog Number: ELK-ES9143
Reactivity: Human
Applications: IHC-p
Information
Request Manual ELK-
Questions? Contact us!
Reactivity: Human
Applications: IHC-p
Information
Request Manual ELK-
Questions? Contact us!
Background:
FAT atypical cadherin 1(FAT1) Homo sapiens This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described. [provided by RefSeq, Jul 2008],
Immunogen: Synthesized peptide derived from human protein . at AA range: 1140-1220
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 504
GeneID: FAT1 CDHF7 FAT
Storage: -20°C/1 year
NOTE: For Research Use Only
FAT atypical cadherin 1(FAT1) Homo sapiens This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described. [provided by RefSeq, Jul 2008],
Immunogen: Synthesized peptide derived from human protein . at AA range: 1140-1220
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 504
GeneID: FAT1 CDHF7 FAT
Storage: -20°C/1 year
NOTE: For Research Use Only
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