FBL antibody (clone 30000000000), anti-human

Background:
This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin.

Other Names:
rRNA 2'-O-methyltransferase fibrillarin, 211-, 34 kDa nucleolar scleroderma antigen, Histone-glutamine methyltransferase, FBL, FIB1, FLRN

Antigen Type:
Recombinant Protein

Gene Name: FBL (HGNC:3599)
Gene ID: 2091
NCBI Accession: NP_001427.2
Primary Accession: P22087
Other Accession: BC019260
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .