FBL polyclonal, anti-human, mouse, monkey

Background:
This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin.

Synonyms: FIB, FLRN, RNU3IP1

Cellular Location: Nucleus nucleolus

Immunogen:
Recombinant protein of human FBL

Gene Symbol: FBL

Gene ID: 2091

Swiss prot: P22087

Calculated MW: 34kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-200, IP 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.