FBLIM1 polyclonal (C-term), anti-human

FBLIM1 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP12719b
Catalog Number: AC-AP12719b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB32318
Applications: IHC-P, WB
Datasheet

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Background:
This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.

Other Names:
Filamin-binding LIM protein 1, FBLP-1, Migfilin, Mitogen-inducible 2-interacting protein, MIG2-interacting protein, FBLIM1, FBLP1

Target/Specificity:
This FBLIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 294-323 amino acids from the C-terminal region of human FBLIM1.

Antigen Region:
294-323

Antigen Type: Synthetic Peptide

Gene Name: FBLIM1
Gene ID: 54751
Primary Accession: Q8WUP2
NCBI Accession: NP_001019386.1;NP_001019387.1;NP_060026.2
Other Accession: NP_001019386.1;NP_060026.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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