FBN1 Polyclonal Antibody

Background:
This gene encodes a member of the fibrillin family. The encoded protein is a large, extracellular matrix glycoprotein that serve as a structural component of 10-12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. Mutations in this gene are associated witHuman, Mousearfan syndrome, isolated ectopia lentis, autosomal dominant Weill-Marchesani syndrome, MASS syndrome, and Shprintzen-Goldberg craniosynostosis syndrome.

Research Area: Cancer, Signal Transduction

Synonyms:
350 kDa glycoprotein component extracellular microfibril, ACMICD, FBN 1, FBN, FBN1, FBN1, Fibrillin 15, Fibrillin-1, Fibrillin1, Fibrillin15, GPHYSD2, Marfan syndrome, MASS, MFS 1, MFS1, OCTD, SGS, SSKS, Weill Marchesani syndrome, WMS, WMS2

Immunogen: Synthetic peptide of human FBN1

Swissprot: P35555
Gene Accession: NP_000129

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.5 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-7540/sc-7541