FBP1 polyclonal, anti-human, mouse, rat

Background:
Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene.

Synonyms: CAB, EIF3A, eIF-6, p27BBP, ITGB4BP, b(2)gcn, p27(BBP)

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human FBP1

Gene Symbol: FBP1

Gene ID: 2203

Swiss prot: P09467

Calculated MW: 27kDa

Recommended dilution:
WB 1:500-2000, IHC 1:20-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.