FBXO31 Polyclonal Antibody

Background:
This gene is a member of the F-box family. Members are classified into three classes according to the substrate interaction domain, FBW for WD40 repeats, FBL for leucing-rich repeats, and FBXO for other domains. This protein, classified into the last category because of the lack of a recognizable substrate binding domain, has been proposed to be a component of the SCF ubiquitination complex. It is thought to bind and recruit substrate for ubiquitination and degradation. This protein may have a role in regulating the cell cycle as well as dendrite growth and neuronal migration. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Cell biology

Synonyms:
DKFZp434B027, DKFZp434J1815, F box only protein 31, F box protein 31, F-box only protein 31, FBX14, FBX31, FBX31, FBXO14, Fbxo31, FLJ22477, MGC15419, MGC9527, pp2386, Putative breast cancer tumor suppressor, SCF ubiquitin ligase specificity factor

Immunogen: Synthetic peptide of human FBXO31

Swissprot: Q5XUX0
Gene Accession: NP_079011

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.7 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-164374