FBXO45 Polyclonal Antibody

Background:
Members of the F-box protein family, such as FBXO45, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (summary by Jin et al., 2004 [PubMed 15520277]).

Research Area: Cell Biology, Epigenetics and Nuclear Signaling, Developmental biology

Synonyms:
F box protein 45, F-box only protein 45, F-box/SPRY domain-containing protein 1, FBSP1, FBX45, fbxo45, hFbxo45

Immunogen: Synthetic peptide of human FBXO45

Swissprot: P0C2W1
Gene Accession: NP001099043

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.2 mg/mL
Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.