FBXO8 Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP18733c
Background:
This gene encodes a member of the F-box protein familywhich is characterized by an approximately 40 amino acid motif, theF-box. The F-box proteins constitute one of the four subunits ofthe ubiquitin protein ligase complex called SCFs(SKP1-cullin-F-box), which function in phosphorylation-dependentubiquitination. The F-box proteins are divided into 3 classes: Fbwscontaining WD-40 domains, Fbls containing leucine-rich repeats, andFbxs containing either different protein-protein interactionmodules or no recognizable motifs. The protein encoded by this genebelongs to the Fbxs class. It contains a C-terminal amino acidsequence that bears a significant similarity with a portion ofyeast Sec7p, a critical regulator of vesicular protein transport.This human protein may interact with ADP-ribosylationfactor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchangefactor) activity.
Other Names:
F-box only protein 8, F-box/SEC7 protein FBS, FBXO8, FBS, FBX8
Gene Name: FBXO8
Gene ID: 26269
Primary Accession: Q9NRD0
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a member of the F-box protein familywhich is characterized by an approximately 40 amino acid motif, theF-box. The F-box proteins constitute one of the four subunits ofthe ubiquitin protein ligase complex called SCFs(SKP1-cullin-F-box), which function in phosphorylation-dependentubiquitination. The F-box proteins are divided into 3 classes: Fbwscontaining WD-40 domains, Fbls containing leucine-rich repeats, andFbxs containing either different protein-protein interactionmodules or no recognizable motifs. The protein encoded by this genebelongs to the Fbxs class. It contains a C-terminal amino acidsequence that bears a significant similarity with a portion ofyeast Sec7p, a critical regulator of vesicular protein transport.This human protein may interact with ADP-ribosylationfactor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchangefactor) activity.
Other Names:
F-box only protein 8, F-box/SEC7 protein FBS, FBXO8, FBS, FBX8
Gene Name: FBXO8
Gene ID: 26269
Primary Accession: Q9NRD0
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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