FBXO8 antibody (clone 1C11), anti-human
€435.00
In stock
SKU
AC-AT2022a
Catalog Number: AC-AT2022a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
Request Information AC-AT2022a">Request Information
Background:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.
Other Names:
F-box only protein 8, F-box/SEC7 protein FBS, FBXO8, FBS, FBX8
Antigen Type:
Recombinant Protein
Gene Name: FBXO8
Gene ID: 26269
NCBI Accession: NP_036312.2
Primary Accession: Q9NRD0
Other Accession: NM_012180
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.
Other Names:
F-box only protein 8, F-box/SEC7 protein FBS, FBXO8, FBS, FBX8
Antigen Type:
Recombinant Protein
Gene Name: FBXO8
Gene ID: 26269
NCBI Accession: NP_036312.2
Primary Accession: Q9NRD0
Other Accession: NM_012180
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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