FBXO8 polyclonal (Center), anti-mouse
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In stock
SKU
AC-AP18733c
Catalog Number: AC-AP18733c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB37321
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB37321
Applications: WB
Datasheet
Request Information
Background:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.
Other Names:
F-box only protein 8, F-box/SEC7 protein FBS, FBXO8, FBS, FBX8
Target/Specificity:
This FBXO8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-195 amino acids from the Central region of human FBXO8.
Antigen Region:
168-195
Antigen Type: Synthetic Peptide
Gene Name: FBXO8
Gene ID: 26269
Primary Accession: Q9NRD0
NCBI Accession: NP_036312.2
Other Accession: Q9QZN3; Q5E9G6; NP_036312.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.
Other Names:
F-box only protein 8, F-box/SEC7 protein FBS, FBXO8, FBS, FBX8
Target/Specificity:
This FBXO8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-195 amino acids from the Central region of human FBXO8.
Antigen Region:
168-195
Antigen Type: Synthetic Peptide
Gene Name: FBXO8
Gene ID: 26269
Primary Accession: Q9NRD0
NCBI Accession: NP_036312.2
Other Accession: Q9QZN3; Q5E9G6; NP_036312.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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