FBXW12 polyclonal (C-term), anti-human

FBXW12 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP10268b
Catalog Number: AC-AP10268b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB27619
Applications: FC, IHC-P, WB
Datasheet

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Background:
Members of the F-box protein family, such as FBXW12, arecharacterized by an approximately 40-amino acid F-box motif. SCFcomplexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM603034), and F-box proteins, act as protein-ubiquitin ligases.F-box proteins interact with SKP1 through the F box, and theyinteract with ubiquitination targets through other proteininteraction domains (Jin et al., 2004 [PubMed 15520277]).[suppliedby OMIM].

Other Names:
F-box/WD repeat-containing protein 12, F-box and WD-40 domain-containing protein 12, F-box only protein 35, FBXW12, FBW12, FBXO12, FBXO35

Target/Specificity:
This FBXW12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-320 amino acids from the C-terminal region of human FBXW12.

Antigen Region:
291-320

Antigen Type: Synthetic Peptide

Gene Name: FBXW12
Gene ID: 285231
Primary Accession: Q6X9E4
NCBI Accession: NP_001153399.1;NP_001153401.1;NP_996985.2
Other Accession: NP_001153399.1;NP_001153401.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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