FBXW5 polyclonal(Center), anti-human
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In stock
SKU
AC-AP19495C
Catalog Number: AC-AP19495C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB40653
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB40653
Applications: WB
Datasheet
Request Information
Background:
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented.
Other Names:
F-box/WD repeat-containing protein 5, F-box and WD-40 domain-containing protein 5, FBXW5, FBW5
Target/Specificity:
This FBXW5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-350 amino acids from the Central region of human FBXW5.
Antigen Region:
324-350
Antigen Type: Synthetic Peptide
Gene Name: FBXW5
Gene ID: 54461
Primary Accession: Q969U6
NCBI Accession: NP_061871.1
Other Accession: NP_061871.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented.
Other Names:
F-box/WD repeat-containing protein 5, F-box and WD-40 domain-containing protein 5, FBXW5, FBW5
Target/Specificity:
This FBXW5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-350 amino acids from the Central region of human FBXW5.
Antigen Region:
324-350
Antigen Type: Synthetic Peptide
Gene Name: FBXW5
Gene ID: 54461
Primary Accession: Q969U6
NCBI Accession: NP_061871.1
Other Accession: NP_061871.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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