FCAR Polyclonal Antibody

Background:
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Research Area: Cancer, Immunology

Synonyms:
FCAR, CD89, CTB-61M7.2, FcalphaRI

Immunogen: A synthetic Peptide of human FCAR

Swissprot: P24071
Gene ID: 2204

Calculated MW: 19-32 kDa
Observed MW: 40 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:200-1:1000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.