FCAR polyclonal (Center), anti-human

FCAR polyclonal (Center), anti-human

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In stock
SKU
AC-AP12915c
Catalog Number: AC-AP12915c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB21753
Applications: WB
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Background:
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Other Names:
Immunoglobulin alpha Fc receptor, IgA Fc receptor, CD89, FCAR, CD89

Target/Specificity:
This FCAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-84 amino acids from the Central region of human FCAR.

Antigen Region:
58-84

Antigen Type: Synthetic Peptide

Gene Name: FCAR
Gene ID: 2204
Primary Accession: P24071
NCBI Accession: NP_001991.1;NP_579803.1;NP_579805.1;NP_579806.1;NP_579807.1;NP_579808.1;NP_579811.1;NP_579812.1;NP_579813.1
Other Accession: NP_579805.1;NP_579803.1;NP_001991.1;NP_579813.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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