CD64a (FCGR1A) polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6238
Background:
Three different classes of IgG Fc receptors have been described: FcγRI (CD64), FcγRII (CD32) and FcγRIII (CD16). The low affinity receptors, CD64 and CD16, have a putative role in mediating humoral immune responses. CD64 is a surface glycoprotein with high affinity for monomeric IgG, is expressed constitutively on monocytes and macrophages, and can be induced in neutrophils subsequent to IFN-γ stimulation. CD64 plays a putative role in the initiation of cell-mediated cytotoxicity.
Alternative Name:
CD64, CD64A, Fc fragment of IgG high affinity Ia receptor (CD64), Fc gamma receptor, Fc gamma receptor I A1, Fc gamma RI, Fc gamma RIA, Fc-gamma RI, Fc-gamma RIA, FCG1, FcgammaRIa, FCGR1, FCGR1, FCGR1A, FcRI, FLJ18345, High affinity immunoglobulin gamma Fc receptor I, IGFR1, IgG Fc receptor I,
Application Dilution: WB: 1:500~1:2000
Specificity: FCGR1A polyclonal antibody detects endogenous levels of FCGR1A protein.
Immunogen:
Recombinant full length Human FCGR1A.
MW: ~39,43 kDa
Swis Prot.: P12314
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Three different classes of IgG Fc receptors have been described: FcγRI (CD64), FcγRII (CD32) and FcγRIII (CD16). The low affinity receptors, CD64 and CD16, have a putative role in mediating humoral immune responses. CD64 is a surface glycoprotein with high affinity for monomeric IgG, is expressed constitutively on monocytes and macrophages, and can be induced in neutrophils subsequent to IFN-γ stimulation. CD64 plays a putative role in the initiation of cell-mediated cytotoxicity.
Alternative Name:
CD64, CD64A, Fc fragment of IgG high affinity Ia receptor (CD64), Fc gamma receptor, Fc gamma receptor I A1, Fc gamma RI, Fc gamma RIA, Fc-gamma RI, Fc-gamma RIA, FCG1, FcgammaRIa, FCGR1, FCGR1, FCGR1A, FcRI, FLJ18345, High affinity immunoglobulin gamma Fc receptor I, IGFR1, IgG Fc receptor I,
Application Dilution: WB: 1:500~1:2000
Specificity: FCGR1A polyclonal antibody detects endogenous levels of FCGR1A protein.
Immunogen:
Recombinant full length Human FCGR1A.
MW: ~39,43 kDa
Swis Prot.: P12314
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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