FCGR3A polyclonal (C-term), anti-human
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In stock
SKU
AC-AP13534b
Catalog Number: AC-AP13534b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33601
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33601
Applications: WB
Datasheet
Request Information
Background:
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Other Names:
Low affinity immunoglobulin gamma Fc region receptor III-A, CD16a antigen, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcR-10, IgG Fc receptor III-2, CD16a, FCGR3A, CD16A, FCG3, FCGR3, IGFR3
Target/Specificity:
This FCGR3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-254 amino acids from the C-terminal region of human FCGR3A.
Antigen Region:
226-254
Antigen Type: Synthetic Peptide
Gene Name: FCGR3A {ECO:0000303|PubMed:23006327}
Gene ID: 2214
Primary Accession: P08637
NCBI Accession: NP_000560.5;NP_001121064.1;NP_001121065.1;NP_001121067.1;NP_001121068.1
Other Accession: NP_001121067.1;NP_001121064.1;NP_000560.5;NP_001121068.1;NP_001121065.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Other Names:
Low affinity immunoglobulin gamma Fc region receptor III-A, CD16a antigen, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcR-10, IgG Fc receptor III-2, CD16a, FCGR3A, CD16A, FCG3, FCGR3, IGFR3
Target/Specificity:
This FCGR3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-254 amino acids from the C-terminal region of human FCGR3A.
Antigen Region:
226-254
Antigen Type: Synthetic Peptide
Gene Name: FCGR3A {ECO:0000303|PubMed:23006327}
Gene ID: 2214
Primary Accession: P08637
NCBI Accession: NP_000560.5;NP_001121064.1;NP_001121065.1;NP_001121067.1;NP_001121068.1
Other Accession: NP_001121067.1;NP_001121064.1;NP_000560.5;NP_001121068.1;NP_001121065.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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