FCGRT polyclonal, anti-human

Quantity: 100 µg

Background:
IgG receptor FcRn large subunit p51 is a protein that in humans is encoded by the FCGRT gene. This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. In addition, it is postulated that long-range cis inactivation of the FCGRT gene is responsible for hypercatabolism of IgG in myotonic dystrophy. The FCGRT gene is closely situated to the DMPK gene, which is mutant in DM. 

Description:
Rabbit IgG polyclonal antibody for IgG receptor FcRn large subunit p51 (FCGRT) detection. Tested with WB, IHC-P in Human.

Synonyms:
Alpha chain antibody, Fc fragment of IgG, receptor transporter, alpha antibody, FCGRN_HUMAN antibody, FCGRT antibody, FcRn alpha chain antibody, FcRn antibody, FCRN, alpha chain antibody, IgG Fc fragment receptor transporter alpha chain antibody, IgG Gc receptor antibody, IgG receptor FcRn large subunit p51 antibody, IgG receptor FcRn large subunit p51 precursor antibody, Immunoglobulin receptor, intestinal, heavy chain antibody, Neonatal Fc receptor antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E. coli-derived human FCGRT recombinant protein (Position: Q56-E291). Human FCGRT shares 70.2% and 68.9% amino acid (aa) sequence identity with mouse and rat FCGRT, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.