FCN3 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP12561b
Catalog Number: AC-AP12561b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31101
Applications: WB, FC, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31101
Applications: WB, FC, IHC-P
Datasheet
Request Information
Background:
Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human serum, there are two types of ficolins, both of which have lectin activity. The protein encoded by this gene is a thermolabile beta-2-macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. The protein, which was initially identified based on its reactivity with sera from patients with systemic lupus erythematosus, has been shown to have a calcium-independent lectin activity. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Alternative splicing occurs at this locus and two variants, each encoding a distinct isoform, have been identified.
Other Names:
Ficolin-3, Collagen/fibrinogen domain-containing lectin 3 p35, Collagen/fibrinogen domain-containing protein 3, Hakata antigen, FCN3, FCNH, HAKA1
Target/Specificity:
This FCN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-243 amino acids from the C-terminal region of human FCN3.
Antigen Region:
214-243
Antigen Type: Synthetic Peptide
Gene Name: FCN3
Gene ID: 8547
Primary Accession: O75636
NCBI Accession: NP_003656.2;NP_775628.1
Other Accession: NP_775628.1;NP_003656.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human serum, there are two types of ficolins, both of which have lectin activity. The protein encoded by this gene is a thermolabile beta-2-macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. The protein, which was initially identified based on its reactivity with sera from patients with systemic lupus erythematosus, has been shown to have a calcium-independent lectin activity. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Alternative splicing occurs at this locus and two variants, each encoding a distinct isoform, have been identified.
Other Names:
Ficolin-3, Collagen/fibrinogen domain-containing lectin 3 p35, Collagen/fibrinogen domain-containing protein 3, Hakata antigen, FCN3, FCNH, HAKA1
Target/Specificity:
This FCN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-243 amino acids from the C-terminal region of human FCN3.
Antigen Region:
214-243
Antigen Type: Synthetic Peptide
Gene Name: FCN3
Gene ID: 8547
Primary Accession: O75636
NCBI Accession: NP_003656.2;NP_775628.1
Other Accession: NP_775628.1;NP_003656.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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