FDFT1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7976
Background:
Several proteins mediate the biosynthesis of cholesterol. The first specific step in the cholesterol biosynthetic pathway is the conversion of transfarnesyl-diphosphate to Squalene, which is catalyzed by the endoplasmic reticulum membrane-associated enzyme Squalene synthetase, also designated Squalene synthase and Farnesyl-diphosphate farnesyltransferase. Squalene synthetase is located at a branch point in the mevalonate pathway and is also involved in isoprenoid biosynthesis. Squalene epoxidase, also designated Squalene monooxygenase, is a multi-pass microsomal membrane-associated enzyme that catalyzes the first oxygenation step in sterol biosynthesis and most likely functions as one of the rate-limiting enzymes in this pathway. Squalene epoxidase may form a complex with Squalene synthetase.
Alternative Name:
DGPT, ERG9, Farnesyl diphosphate farnesyltransferase 1, Farnesyl diphosphate farnesyltransferase, Farnesyl-diphosphate farnesyltransferase, FDFT_HUMAN, FDFT1, FPP:FPP farnesyltransferase, Presqualene di diphosphate synthase, SQS, Squalene synthase, Squalene synthetase, SS,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: FDFT1 polyclonal antibody detects endogenous levels of FDFT1 protein.
Immunogen:
Recombinant full length Human FDFT1.
MW: ~ 48 kDa
Swis Prot.: P37268
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Several proteins mediate the biosynthesis of cholesterol. The first specific step in the cholesterol biosynthetic pathway is the conversion of transfarnesyl-diphosphate to Squalene, which is catalyzed by the endoplasmic reticulum membrane-associated enzyme Squalene synthetase, also designated Squalene synthase and Farnesyl-diphosphate farnesyltransferase. Squalene synthetase is located at a branch point in the mevalonate pathway and is also involved in isoprenoid biosynthesis. Squalene epoxidase, also designated Squalene monooxygenase, is a multi-pass microsomal membrane-associated enzyme that catalyzes the first oxygenation step in sterol biosynthesis and most likely functions as one of the rate-limiting enzymes in this pathway. Squalene epoxidase may form a complex with Squalene synthetase.
Alternative Name:
DGPT, ERG9, Farnesyl diphosphate farnesyltransferase 1, Farnesyl diphosphate farnesyltransferase, Farnesyl-diphosphate farnesyltransferase, FDFT_HUMAN, FDFT1, FPP:FPP farnesyltransferase, Presqualene di diphosphate synthase, SQS, Squalene synthase, Squalene synthetase, SS,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: FDFT1 polyclonal antibody detects endogenous levels of FDFT1 protein.
Immunogen:
Recombinant full length Human FDFT1.
MW: ~ 48 kDa
Swis Prot.: P37268
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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