FDPS polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP2418b
Catalog Number: AC-AP2418b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB04786
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB04786
Applications: WB, IHC-P
Datasheet
Request Information
Background:
The isoprene biosynthetic pathway supply the cell with cholesterol, ubiquinone, and various nonsterol metabolites. The farnesylpyrophosphate synthetase enzyme catalyzes the formation of geranyl and farnesylpyrophosphate from isopentenylpyrophosphate and dimethylallyl pyrophosphate. Analysis of FDPS activity and protein in rat liver, accompanied by immunofluorescence and immunoelectron microscopy studies, demonstrated that FDPS is predominantly localized in peroxisomes.1 Liver tissue from patients with the peroxisomal deficiency diseases Zellweger syndrome and neonatal adrenoleukodystrophy exhibit diminished activities of FDPS and subsequent isoprenoid synthesis.
Other Names:
Farnesyl pyrophosphate synthase, FPP synthase, FPS, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Geranyltranstransferase, FDPS, FPS, KIAA1293
Target/Specificity:
This FDPS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-419 amino acids from the center region of human FDPS.
Antigen Region:
389-419
Antigen Type: Synthetic Peptide
Gene Name: FDPS (HGNC:3631)
Gene ID: 2224
Primary Accession: P14324
NCBI Accession: NP_001129293.1;NP_001129294.1;NP_001229753.1;NP_001229754.1;NP_001995.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
The isoprene biosynthetic pathway supply the cell with cholesterol, ubiquinone, and various nonsterol metabolites. The farnesylpyrophosphate synthetase enzyme catalyzes the formation of geranyl and farnesylpyrophosphate from isopentenylpyrophosphate and dimethylallyl pyrophosphate. Analysis of FDPS activity and protein in rat liver, accompanied by immunofluorescence and immunoelectron microscopy studies, demonstrated that FDPS is predominantly localized in peroxisomes.1 Liver tissue from patients with the peroxisomal deficiency diseases Zellweger syndrome and neonatal adrenoleukodystrophy exhibit diminished activities of FDPS and subsequent isoprenoid synthesis.
Other Names:
Farnesyl pyrophosphate synthase, FPP synthase, FPS, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Geranyltranstransferase, FDPS, FPS, KIAA1293
Target/Specificity:
This FDPS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-419 amino acids from the center region of human FDPS.
Antigen Region:
389-419
Antigen Type: Synthetic Peptide
Gene Name: FDPS (HGNC:3631)
Gene ID: 2224
Primary Accession: P14324
NCBI Accession: NP_001129293.1;NP_001129294.1;NP_001229753.1;NP_001229754.1;NP_001995.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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