FECH polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71214
Background:
The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.
Alternative Name:
Heme synthase, Protoheme ferro-lyase
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: FECH polyclonal antibody detects endogenous levels of FECH protein.
Immunogen:
Recombinant protein of human FECH.
MW: ~ 48 kDa
Swis Prot.: P22830
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.
Alternative Name:
Heme synthase, Protoheme ferro-lyase
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: FECH polyclonal antibody detects endogenous levels of FECH protein.
Immunogen:
Recombinant protein of human FECH.
MW: ~ 48 kDa
Swis Prot.: P22830
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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