FECH Polyclonal Antibody

Background:
The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.

Research Area: Cardiovascular, Metabolism

Synonyms:
EPP, FCE, Fch, Fcl, fech, Ferrochelatase (protoporphyria), Ferrochelatase, Ferrochelatase mitochondrial, Heme synthase, Heme synthetase, HEMH, mitochondrial, Protoheme ferro lyase, Protoheme ferro-lyase, Protoporphyria

Immunogen: Synthetic peptide of human FECH

Swissprot: P22830
Gene Accession: NP000131

Calculated MW: 48 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.56 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.