FEM1B Blocking Peptide (C-Term)

Background:
Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1.

Other Names:
Protein fem-1 homolog B, FEM1b, FEM1-beta, Fem-1-like death receptor-binding protein alpha, Fem-1-like in apoptotic pathway protein alpha, F1A-alpha, FEM1B, F1AA, KIAA0396

Target/Specificity:
The synthetic peptide sequence is selected from aa 567-579 of HUMAN FEM1B

Gene Name: FEM1B {ECO:0000303|PubMed:10623617, ECO:0000312|HGNC:HGNC:3649}

Gene ID: 10116
Primary Accession: Q9UK73
Other Accession: Q9Z2G0;P0C6P7
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.