FEM1B polyclonal (C-Term), anti-human, mouse, rat

Background:
Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1.

Other Names:
Protein fem-1 homolog B, FEM1b, FEM1-beta, Fem-1-like death receptor-binding protein alpha, Fem-1-like in apoptotic pathway protein alpha, F1A-alpha, FEM1B, F1AA, KIAA0396

Target/Specificity:
This FEM1B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 547-579 amino acids from human FEM1B.

Antigen Type: Synthesized Peptide

Gene Name: FEM1B {ECO:0000303|PubMed:10623617, ECO:0000312|HGNC:HGNC:3649}
Gene ID: 10116
Primary Accession: Q9UK73
Other Accession: Q9Z2G0;P0C6P7
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.