FES polyclonal, anti-human, mouse

Background:
This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.

Synonyms: FPS

Cellular Location: Cell junction Cell membrane Cytoplasm Cytoplasmic side Cytoplasmic vesicle Golgi apparatus Peripheral membrane protein cytoskeleton cytosol focal adhesion

Immunogen:
Recombinant protein of human FES

Gene Symbol: FES

Gene ID: 2242

Swiss prot: P07332

Calculated MW: 93kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.