FES polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
FES(feline sarcoma oncogene) is an enzyme that in humans is encoded by the FES gene, also known as Proto-oncogene tyrosine-protein kinase Fes/Fps, Feline sarcoma/Fujinami avian sarcoma oncogene homolog, Proto-oncogene c-Fes, Proto-oncogene c-Fps, p93c-fes c-fes/fps protein, FPS, Oncogene FES, feline sarcoma virus, FPS. This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. Non-onc intervening sequences were present in the human counterpart. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia, but it is also involved in normal hematopoiesis. A truncated transcript has been identified that is generated utilizing a start site in one of the far downstream exons but a protein product associated with this transcript has not been identified.

Description:
Rabbit IgG polyclonal antibody for Tyrosine-protein kinase Fes/Fps (FES) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
c-fes/fps protein antibody, cFES antibody, feline sarcoma(Snyder-Theilen) viral(v-fes)/Fujinami antibody, Feline sarcoma oncogene antibody, fes antibody, FES_HUMAN antibody, FPS antibody, Oncogene FES antibody, Oncogene FES feline sarcoma virus antibody, Proto oncogene tyrosine protein kinase Fes/Fps antibody, Proto-oncogene c-Fes antibody, Proto-oncogene c-Fps antibody, proto-oncogene tyrosine-protein kinase Fes/Fps antibody, Tyrosine-protein kinase Fes/Fps antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human FES(644-663aa FLTFLRTEGARLRVKTLLQM), identical to the related mouse and rat sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human.
Predicted to work with: mouse, rat.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.