FES Polyclonal Antibody

Background:
This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.

Research Area: Cancer, Signal Transduction

Synonyms:
FES, FPS

Immunogen: Recombinant fusion protein of human FES (NP_001137256.1).

Swissprot: P07332
Gene ID: 2242

Calculated MW: 78 kDa/85 kDa/86 kDa/93 kDa
Observed MW: 98 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.