FGA monoclonal (N-term), anti-human, mouse
€0.00
In stock
SKU
AC-AM2051B
Catalog Number: AC-AM2051B
Size: 80 µl, 400 µl
Isotype: mouse IgM
Clone Name: 471CT12.1.2
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: mouse IgM
Clone Name: 471CT12.1.2
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq].
Other Names:
Fibrinogen alpha chain, Fibrinopeptide A, Fibrinogen alpha chain, FGA
Target/Specificity:
This FGA antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 420-448 amino acids from the N-terminal region of human FGA.
Antigen Region:
420-448
Antigen Type: Synthetic Peptide
Gene Name: FGA
Gene ID: 2243
Primary Accession: P02671
NCBI Accession: NP_000499.1;NP_068657.1
Other Accession: NP_000499.1
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq].
Other Names:
Fibrinogen alpha chain, Fibrinopeptide A, Fibrinogen alpha chain, FGA
Target/Specificity:
This FGA antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 420-448 amino acids from the N-terminal region of human FGA.
Antigen Region:
420-448
Antigen Type: Synthetic Peptide
Gene Name: FGA
Gene ID: 2243
Primary Accession: P02671
NCBI Accession: NP_000499.1;NP_068657.1
Other Accession: NP_000499.1
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
| Is Featured? | No |
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