FGB Polyclonal Antibody

Background:
The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.

Research Area: Cardiovascular

Synonyms:
Epididymis secretory sperm binding protein Li 78p, FGB, FIBB, Fibrinogen B beta polypeptide, Fibrinogen beta chain, Fibrinogen beta polypeptide chain, Fibrinopeptide B, HEL S 78p, Liver regeneration-related protein LRRG036/LRRG043/LRRG189, MGC104327, MGC120405, OTTHUMP00000197066

Immunogen: Recombinant protein of human FGB

Swissprot: P02675
Gene Accession: BC106760

Calculated MW: 56 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:1000-1:5000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-18027/sc-33581/sc-33581