FGB Polyclonal Antibody

Background:
The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.

Research Area: Cardiovascular, Metabolism

Synonyms:
Beta fibrinogen, Epididymis Secretory Sperm Binding Protein Li 78p, FGB, Fibrinogen beta chain, HEL-S-78p

Immunogen: Recombinant Human Fibrinogen beta chain protein

Swissprot: P02675
Gene ID: 2244

Calculated MW: 55 kDa
Observed MW: 55 kDa

Purification Method: Antigen Affinity Purification

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: WB 1:2000-1:4000 IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.