FGF-19 (clone FG98-6), anti-human
€204.00
In stock
SKU
ARP-23-A0065
Catalog Number: 23-A0065
Size: 25 µg
Isotype: Mouse IgG2b kappa
Size: 25 µg
Isotype: Mouse IgG2b kappa
Decription:
FGF-19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB.
Synonyms: Fibroblast Growth Factor 19
Clone: FG98-6
Isotype: Mouse IgG2b kappa
Immunogen: Recombinant human FGF-19.
Reactivity: human
Specificity: Recognizes human FGF-19. Detects a band of ~25kDa by Western blot.
Form: Purified, in 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Applications:
ELISA: (direct or indirect: 1:2'000-1:5'000)
Western blot: (1:2'000-1:5'000 using ECL. Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature).
Working Dilution: Optimal conditions must be determined individually for each application.
Concentration: 1mg/ml
Storage: 2-8C immediate use, or -20C (aliquote)
FGF-19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB.
Synonyms: Fibroblast Growth Factor 19
Clone: FG98-6
Isotype: Mouse IgG2b kappa
Immunogen: Recombinant human FGF-19.
Reactivity: human
Specificity: Recognizes human FGF-19. Detects a band of ~25kDa by Western blot.
Form: Purified, in 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Applications:
ELISA: (direct or indirect: 1:2'000-1:5'000)
Western blot: (1:2'000-1:5'000 using ECL. Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature).
Working Dilution: Optimal conditions must be determined individually for each application.
Concentration: 1mg/ml
Storage: 2-8C immediate use, or -20C (aliquote)
| Is Featured? | No |
|---|
Write Your Own Review